| AT4G23100 | glutamate-cysteine ligase glutamate-cysteine ligase (GSH1); FUNCTIONS IN: glutamate-cysteine ligase activity; INVOLVED IN: in 13 processes; LOCATED IN: chloroplast stroma, chloroplast; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Glutamate--cysteine ligase, GCS2 (InterPro:IPR006336), Glutamate--cysteine ligase, plant (InterPro:IPR011556); Has 2650 Blast hits to 2650 proteins in 482 species: Archae - 15; Bacteria - 892; Metazoa - 0; Fungi - 0; Plants - 118; Viruses - 0; Other Eukaryotes - 1625 (source: NCBI BLink). Encodes the enzyme glutamate-cysteine ligase catalyzing the first, and rate-limiting, step of glutathione biosynthesis. Required for cell proliferation at the root tip. Involved in susceptibility to the bacterial pathogen Pseudomonas syringae. Mutants are phytoalexin defective. | 4 | - | View |
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