AT5G24630 | This gene is predicted to encode a protein that forms part of the topoisomerase VI complex. BIN4 is a nuclear-localized protein that can bind DNA. bin4 mutants are brassinolide-insensitive dwarves with severely reduced cell size in leaves, roots, and hypocotyls. Proper development of root hairs and trichomes is also disrupted in bin4 mutants and they have elevated levels of double strand breaks in their cotyledon cells. brassinosteroid-insensitive4 (BIN4); FUNCTIONS IN: double-stranded DNA binding; INVOLVED IN: in 7 processes; LOCATED IN: DNA topoisomerase complex (ATP-hydrolyzing), nucleus; EXPRESSED IN: cotyledon vascular system, cotyledon, root tip, leaf trichome, leaf; Has 3628 Blast hits to 2405 proteins in 320 species: Archae - 6; Bacteria - 1196; Metazoa - 1107; Fungi - 390; Plants - 165; Viruses - 17; Other Eukaryotes - 747 (source: NCBI BLink). double-stranded DNA binding | 5 | - | View |