| AT5G55300 | DNA topoisomerase I alpha Encodes a type-I DNA topoisomerase I. Disruptions in this gene affect phyllotaxis and plant architecture suggesting that the gene plays a critical role in the maintenance of a regular pattern of organ initiation. Isolated as a protein oxidized during seed germination; proteomics approach revealed differences in de novo synthesis levels of this protein in condition with vs. without salicylic acid in the period from 0 to 40 hrs. following seed imbibition. Functions in stem cell maintenance at all stages of shoot and floral meristems and in the regulation of gene silencing. DNA topoisomerase I alpha (TOP1ALPHA); FUNCTIONS IN: protein binding, DNA topoisomerase type I activity; INVOLVED IN: in 8 processes; LOCATED IN: chromosome; EXPRESSED IN: 29 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: DNA topoisomerase I, DNA binding, mixed alpha/beta motif, eukaryotic-type (InterPro:IPR013030), DNA topoisomerase I, DNA binding, eukaryotic-type (InterPro:IPR008336), DNA topoisomerase I, C-terminal (InterPro:IPR001631), DNA topoisomerase I, catalytic core, eukaryotic-type (InterPro:IPR013500), DNA topoisomerase I, active site (InterPro:IPR018521), DNA topoisomerase I, catalytic core, alpha/beta subdomain, eukaryotic-type (InterPro:IPR014727), DNA topoisomerase I, catalytic core, alpha-helical subdomain, eukaryotic-type (InterPro:IPR014711), DNA breaking-rejoining enzyme, catalytic core (InterPro:IPR011010), DNA topoisomerase I, C-terminal, eukaryotic-type (InterPro:IPR013499); BEST Arabidopsis thaliana protein match is: DNA topoisomerase 1 beta (TAIR:AT5G55310.1). | 5 | - | View |
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