| AT5G13300 | ARF GTPase-activating protein SCARFACE (SFC); FUNCTIONS IN: ARF GTPase activator activity, phosphoinositide binding; INVOLVED IN: xylem and phloem pattern formation, response to auxin stimulus, phloem or xylem histogenesis, leaf morphogenesis; LOCATED IN: cytosol, trans-Golgi network transport vesicle, plasma membrane; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Arf GTPase activating protein (InterPro:IPR001164), Pleckstrin homology-type (InterPro:IPR011993), Ankyrin repeat-containing domain (InterPro:IPR020683), BAR (InterPro:IPR004148), Pleckstrin homology (InterPro:IPR001849), Ankyrin repeat (InterPro:IPR002110); BEST Arabidopsis thaliana protein match is: ARF-GAP domain 1 (TAIR:AT5G61980.1); Has 64753 Blast hits to 27558 proteins in 1221 species: Archae - 110; Bacteria - 5131; Metazoa - 34265; Fungi - 4887; Plants - 2591; Viruses - 654; Other Eukaryotes - 17115 (source: NCBI BLink). Belongs to 15-member small GTPase gene family, ARF-GAP domain proteins (AGD); corresponds to AGD3, and is one of four proteins belonging to class 1, together with AGD1, AGD2 and AGD4. The protein contains four domains: BAR domain, PH domain, an ARF-GAP domain, and two Ankyrin repeats. In sfc mutants, the secondary and tertiary veins of cotyledons, leaves, sepals and petals are largely replaced by small segments of discontinuous veins. sfc mutants have exaggerated responses to auxin. | 5 | - | View |
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