Integrative inference of transcriptional networks in Arabidopsis yields novel ROS signalling regulators

This website allows determining the enrichment of TFs associated with (i.e. regulating) a set of input genes.
Enrichment statistics are computed using the hypergeometric distribution combined with Benjamini–Hochberg correction for multiple hypotheses testing (a q-value cutoff of 1e-03 is applied).
'Run associated TF analysis': For a set of input genes, the iGRN is queried to identify all TFs controllering one (or more) of these input genes.

Publications

Citation

  • De Clercq, I., Van de Velde, J., Luo, X., Liu, L., Storme, V., Van Bel, M., Pottie, R., Vaneechoutte, D., Van Breusegem, F., Vandepoele, K. (2020) Integrative inference of transcriptional networks in Arabidopsis yields novel ROS signalling regulators Nat Plants. 2021 Apr;7(4):500-513