- Gene ID
- Ot01g05780
- Locus
- Ot01g05780
- Functional Description
- Thymidylate synthase (ISS)
- Gene Type
- protein-coding gene
- Contig
- chrom01
- Last Modified On
- 08 March 2010 20h26
- History
-
Annotator
- Name
- EuGene Automatic Prediction
- Email
- beg-orcae@psb.ugent.be
- Lab
- UGent
- Status
- active
Gene Actions
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Gene Function
- Short Name
- n/a
- Alternative Names
- n/a
- Definition
- Thymidylate synthase (ISS)
- Additional Functional Description
- n/a
- Pubmed ID
- n/a
- EC Number
- n/a
- KOGid
- n/a
Gene Ontology
- Cellular Component
-
n/a
- Molecular Function
-
1.
thymidylate synthase activity
2.
oxidoreductase activity
- Biological Process
-
1.
dTMP biosynthetic process
2.
metabolic process
Protein Domains
| Domain ID | Description | Database |
|---|
|
G3DSA:3.40.430.10 |
no description |
Gene3D |
|
SSF53597 |
Dihydrofolate reductases |
superfamily |
|
IPR002198 |
Short-chain dehydrogenase/reductase SDR |
InterPro |
|
IPR020940 |
Thymidylate synthase, active site |
InterPro |
|
IPR001796 |
Dihydrofolate reductase domain |
InterPro |
|
PTHR11549 |
DIHYDROFOLATE REDUCTASE |
HMMPanther |
|
IPR017925 |
Dihydrofolate reductase conserved site |
InterPro |
|
IPR016040 |
NAD(P)-binding domain |
InterPro |
|
IPR000398 |
Thymidylate synthase |
InterPro |
Protein Homologs
| ProteinID | Description / BlastScore | Database | Actions |
|---|
| CAL50493.1 |
bifunctional dihydrofolate reductase-thymidylate synthase 2 / DHFR-TS (ISS) [Ostreococcus tauri]
Evalue: 0.0 | Bitscore: 1429
Identities = 731/731 (100%), Positives = 731/731 (100%), Gaps = 0/731 (0%) |
NCBI |
Show Blast
|
| XP_001417778.1 |
predicted protein [Ostreococcus lucimarinus CCE9901]
Evalue: 0.0 | Bitscore: 935
Identities = 450/494 (91%), Positives = 474/494 (95%), Gaps = 0/494 (0%) |
NCBI |
Show Blast
|
| EEH58542.1 |
bifunctional dihydrofolate reductase-thymidylate synthase [Micromonas pusilla CCMP1545]
Evalue: 0.0 | Bitscore: 743
Identities = 362/515 (70%), Positives = 407/515 (79%), Gaps = 19/515 (3%) |
NCBI |
Show Blast
|
| XP_002502546.1 |
bifunctional dihydrofolate reductase-thymidylate synthase [Micromonas sp. RCC299]
Evalue: 0.0 | Bitscore: 741
Identities = 366/516 (70%), Positives = 412/516 (79%), Gaps = 19/516 (3%) |
NCBI |
Show Blast
|
| Q05763 |
Bifunctional dihydrofolate reductase-thymidylate synthase 2 OS=Arabidopsis thaliana GN=THY-2 PE=2 SV=2
Evalue: 0.0 | Bitscore: 668
Identities = 315/510 (61%), Positives = 371/510 (72%), Gaps = 26/510 (5%) |
SwissP |
Show Blast
|
| AT4G34570.1 |
| Symbols: THY-2 | THY-2 (THYMIDYLATE SYNTHASE 2) | chr4:16511134-16514115 REVERSE
Evalue: 0.0 | Bitscore: 668
Identities = 315/510 (61%), Positives = 371/510 (72%), Gaps = 26/510 (5%) |
Tair |
Show Blast
|
| EEE53150.1 |
hypothetical protein OsJ_35972 [Oryza sativa Japonica Group]
Evalue: 0.0 | Bitscore: 665
Identities = 319/516 (61%), Positives = 380/516 (73%), Gaps = 30/516 (5%) |
NCBI |
Show Blast
|
| Q2QRX6 |
Putative bifunctional dihydrofolate reductase-thymidylate synthase OS=Oryza sativa subsp. japonica GN=Os12g0446900 PE=3
Evalue: 0.0 | Bitscore: 664
Identities = 312/503 (62%), Positives = 370/503 (73%), Gaps = 30/503 (5%) |
SwissP |
Show Blast
|
| Q05762 |
Bifunctional dihydrofolate reductase-thymidylate synthase 1 OS=Arabidopsis thaliana GN=THY-1 PE=2 SV=2
Evalue: 0.0 | Bitscore: 660
Identities = 311/510 (60%), Positives = 369/510 (72%), Gaps = 24/510 (4%) |
SwissP |
Show Blast
|
| AT2G16370.1 |
| Symbols: THY-1 | THY-1 (THYMIDYLATE SYNTHASE 1) | chr2:7089120-7091415 REVERSE
Evalue: 0.0 | Bitscore: 660
Identities = 311/510 (60%), Positives = 369/510 (72%), Gaps = 24/510 (4%) |
Tair |
Show Blast
|
| ProteinID | Description / BlastScore | Database | Actions |
|---|
| EAK45408.1 |
unknown [environmental sequence]
Evalue: 1e-168 | Bitscore: 592
Identities = 263/280 (93%), Positives = 273/280 (97%) |
GOS |
Show Blast
|
| EAJ49123.1 |
unknown [environmental sequence]
Evalue: 4e-87 | Bitscore: 322
Identities = 151/282 (53%), Positives = 189/282 (67%), Gaps = 20/282 (7%) |
GOS |
Show Blast
|
| EAD09104.1 |
unknown [environmental sequence]
Evalue: 4e-86 | Bitscore: 319
Identities = 149/276 (53%), Positives = 185/276 (67%), Gaps = 20/276 (7%) |
GOS |
Show Blast
|
| EAH89117.1 |
unknown [environmental sequence]
Evalue: 2e-84 | Bitscore: 313
Identities = 148/283 (52%), Positives = 192/283 (67%), Gaps = 20/283 (7%) |
GOS |
Show Blast
|
| EAJ65473.1 |
unknown [environmental sequence]
Evalue: 5e-84 | Bitscore: 312
Identities = 149/281 (53%), Positives = 194/281 (69%), Gaps = 20/281 (7%) |
GOS |
Show Blast
|
| EAH86759.1 |
unknown [environmental sequence]
Evalue: 5e-84 | Bitscore: 311
Identities = 145/282 (51%), Positives = 191/282 (67%), Gaps = 20/282 (7%) |
GOS |
Show Blast
|
| EAC87197.1 |
unknown [environmental sequence]
Evalue: 9e-84 | Bitscore: 311
Identities = 143/282 (50%), Positives = 193/282 (68%), Gaps = 20/282 (7%) |
GOS |
Show Blast
|
| EAI40988.1 |
unknown [environmental sequence]
Evalue: 1e-83 | Bitscore: 310
Identities = 147/283 (51%), Positives = 191/283 (67%), Gaps = 20/283 (7%) |
GOS |
Show Blast
|
| EAC51221.1 |
unknown [environmental sequence]
Evalue: 7e-83 | Bitscore: 308
Identities = 147/282 (52%), Positives = 189/282 (67%), Gaps = 20/282 (7%) |
GOS |
Show Blast
|
| EAI48378.1 |
unknown [environmental sequence]
Evalue: 9e-83 | Bitscore: 308
Identities = 149/283 (52%), Positives = 197/283 (69%), Gaps = 22/283 (7%) |
GOS |
Show Blast
|
| ProteinID | Description / BlastScore | Database | Actions |
|---|
| CAL50493.1 |
bifunctional dihydrofolate reductase-thymidylate synthase 2 / DHFR-TS (ISS) [Ostreococcus tauri]
Evalue: 0.0 | Bitscore: 1429
Identities = 731/731 (100%), Positives = 731/731 (100%), Gaps = 0/731 (0%) |
NCBI |
Show Blast
|
| XP_001417778.1 |
predicted protein [Ostreococcus lucimarinus CCE9901]
Evalue: 0.0 | Bitscore: 935
Identities = 450/494 (91%), Positives = 474/494 (95%), Gaps = 0/494 (0%) |
NCBI |
Show Blast
|
| EEH58542.1 |
bifunctional dihydrofolate reductase-thymidylate synthase [Micromonas pusilla CCMP1545]
Evalue: 0.0 | Bitscore: 743
Identities = 362/515 (70%), Positives = 407/515 (79%), Gaps = 19/515 (3%) |
NCBI |
Show Blast
|
| XP_002502546.1 |
bifunctional dihydrofolate reductase-thymidylate synthase [Micromonas sp. RCC299]
Evalue: 0.0 | Bitscore: 741
Identities = 366/516 (70%), Positives = 412/516 (79%), Gaps = 19/516 (3%) |
NCBI |
Show Blast
|
| EEE53150.1 |
hypothetical protein OsJ_35972 [Oryza sativa Japonica Group]
Evalue: 0.0 | Bitscore: 665
Identities = 319/516 (61%), Positives = 380/516 (73%), Gaps = 30/516 (5%) |
NCBI |
Show Blast
|
| NP_195183.2 |
THY-2 (thymidylate synthase 2); dihydrofolate reductase/ thymidylate synthase [Arabidopsis thaliana]
Evalue: 0.0 | Bitscore: 655
Identities = 316/511 (61%), Positives = 373/511 (72%), Gaps = 26/511 (5%) |
NCBI |
Show Blast
|
| AAA32789.1 |
dihydrofolate reductase-thymidylate synthase [Arabidopsis thaliana]
Evalue: 0.0 | Bitscore: 654
Identities = 316/511 (61%), Positives = 373/511 (72%), Gaps = 26/511 (5%) |
NCBI |
Show Blast
|
| XP_001758934.1 |
predicted protein [Physcomitrella patens subsp. patens]
Evalue: 0.0 | Bitscore: 652
Identities = 321/508 (63%), Positives = 375/508 (73%), Gaps = 22/508 (4%) |
NCBI |
Show Blast
|
| XP_002280254.1 |
PREDICTED: similar to Bifunctional dihydrofolate reductase-thymidylate synthase [Vitis vinifera]
Evalue: 0.0 | Bitscore: 649
Identities = 312/513 (60%), Positives = 372/513 (72%), Gaps = 27/513 (5%) |
NCBI |
Show Blast
|
| CBI37680.1 |
unnamed protein product [Vitis vinifera]
Evalue: 0.0 | Bitscore: 649
Identities = 308/498 (61%), Positives = 369/498 (74%), Gaps = 19/498 (3%) |
NCBI |
Show Blast
|
| No hits found against database O.RCC809 with an e-value better than 1e-3. |
| No hits found against database O.luci with an e-value better than 1e-3. |
| ProteinID | Description / BlastScore | Database | Actions |
|---|
| Ot08g04120 |
chrom08.0001 [675179..675985]
Evalue: 6e-06 | Bitscore: 48
Identities = 32/93 (34%), Positives = 46/93 (49%), Gaps = 7/93 (7%) |
Self |
Show Blast
|
| Ot02g06690 |
chrom02.0001 [879934..880872] incomplete
Evalue: 2e-05 | Bitscore: 46
Identities = 36/107 (33%), Positives = 49/107 (45%), Gaps = 6/107 (5%) |
Self |
Show Blast
|
| Ot01g05790 |
chrom01.0001 [947060..948027,948060..948063]
Evalue: 2e-05 | Bitscore: 46
Identities = 33/95 (34%), Positives = 44/95 (46%), Gaps = 3/95 (3%) |
Self |
Show Blast
|
| Ot08g00270 |
chrom08.0001 [43784..44665]
Evalue: 0.0002 | Bitscore: 43
Identities = 26/80 (32%), Positives = 39/80 (48%), Gaps = 3/80 (3%) |
Self |
Show Blast
|
| Ot07g00440 |
chrom07.0001 [80303..80737,80889..81770] inframe stop codon
Evalue: 0.0002 | Bitscore: 43
Identities = 31/94 (32%), Positives = 45/94 (47%), Gaps = 7/94 (7%) |
Self |
Show Blast
|
| ProteinID | Description / BlastScore | Database | Actions |
|---|
| Q05763 |
Bifunctional dihydrofolate reductase-thymidylate synthase 2 OS=Arabidopsis thaliana GN=THY-2 PE=2 SV=2
Evalue: 0.0 | Bitscore: 668
Identities = 315/510 (61%), Positives = 371/510 (72%), Gaps = 26/510 (5%) |
SwissP |
Show Blast
|
| Q2QRX6 |
Putative bifunctional dihydrofolate reductase-thymidylate synthase OS=Oryza sativa subsp. japonica GN=Os12g0446900 PE=3
Evalue: 0.0 | Bitscore: 664
Identities = 312/503 (62%), Positives = 370/503 (73%), Gaps = 30/503 (5%) |
SwissP |
Show Blast
|
| Q05762 |
Bifunctional dihydrofolate reductase-thymidylate synthase 1 OS=Arabidopsis thaliana GN=THY-1 PE=2 SV=2
Evalue: 0.0 | Bitscore: 660
Identities = 311/510 (60%), Positives = 369/510 (72%), Gaps = 24/510 (4%) |
SwissP |
Show Blast
|
| O81395 |
Bifunctional dihydrofolate reductase-thymidylate synthase OS=Zea mays GN=DRTS PE=2 SV=1
Evalue: 0.0 | Bitscore: 658
Identities = 311/520 (59%), Positives = 374/520 (71%), Gaps = 30/520 (5%) |
SwissP |
Show Blast
|
| P51820 |
Bifunctional dihydrofolate reductase-thymidylate synthase OS=Glycine max PE=1 SV=1
Evalue: 0.0 | Bitscore: 658
Identities = 307/516 (59%), Positives = 371/516 (71%), Gaps = 30/516 (5%) |
SwissP |
Show Blast
|
| P45350 |
Bifunctional dihydrofolate reductase-thymidylate synthase OS=Daucus carota PE=2 SV=1
Evalue: 0.0 | Bitscore: 639
Identities = 309/517 (59%), Positives = 362/517 (70%), Gaps = 31/517 (5%) |
SwissP |
Show Blast
|
| Q27828 |
Bifunctional dihydrofolate reductase-thymidylate synthase OS=Paramecium tetraurelia GN=GSPATT00019973001 PE=3 SV=1
Evalue: 1e-147 | Bitscore: 523
Identities = 252/496 (50%), Positives = 339/496 (68%), Gaps = 38/496 (7%) |
SwissP |
Show Blast
|
| Q27783 |
Bifunctional dihydrofolate reductase-thymidylate synthase OS=Trypanosoma brucei brucei PE=3 SV=1
Evalue: 1e-136 | Bitscore: 487
Identities = 256/523 (48%), Positives = 324/523 (61%), Gaps = 47/523 (8%) |
SwissP |
Show Blast
|
| Q27793 |
Bifunctional dihydrofolate reductase-thymidylate synthase OS=Trypanosoma cruzi PE=1 SV=2
Evalue: 1e-134 | Bitscore: 478
Identities = 254/518 (49%), Positives = 321/518 (61%), Gaps = 33/518 (6%) |
SwissP |
Show Blast
|
| P07382 |
Bifunctional dihydrofolate reductase-thymidylate synthase OS=Leishmania major PE=1 SV=1
Evalue: 1e-131 | Bitscore: 470
Identities = 252/526 (47%), Positives = 320/526 (60%), Gaps = 58/526 (11%) |
SwissP |
Show Blast
|
| ProteinID | Description / BlastScore | Database | Actions |
|---|
| AT4G34570.1 |
| Symbols: THY-2 | THY-2 (THYMIDYLATE SYNTHASE 2) | chr4:16511134-16514115 REVERSE
Evalue: 0.0 | Bitscore: 668
Identities = 315/510 (61%), Positives = 371/510 (72%), Gaps = 26/510 (5%) |
Tair |
Show Blast
|
| AT2G16370.1 |
| Symbols: THY-1 | THY-1 (THYMIDYLATE SYNTHASE 1) | chr2:7089120-7091415 REVERSE
Evalue: 0.0 | Bitscore: 660
Identities = 311/510 (60%), Positives = 369/510 (72%), Gaps = 24/510 (4%) |
Tair |
Show Blast
|
| AT2G21550.1 |
| Symbols: | bifunctional dihydrofolate reductase-thymidylate synthase, putative / DHFR-TS, putative |
Evalue: 1e-120 | Bitscore: 431
Identities = 214/494 (43%), Positives = 303/494 (61%), Gaps = 37/494 (7%) |
Tair |
Show Blast
|
| AT4G09750.1 |
| Symbols: | short-chain dehydrogenase/reductase (SDR) family protein | chr4:6146767-6148695 FORWARD
Evalue: 2e-15 | Bitscore: 81
Identities = 45/106 (42%), Positives = 66/106 (62%), Gaps = 4/106 (3%) |
Tair |
Show Blast
|
| AT2G29260.1 |
| Symbols: | tropinone reductase, putative / tropine dehydrogenase, putative | chr2:12589600-12591031 FORWARD
Evalue: 1e-07 | Bitscore: 55
Identities = 40/104 (38%), Positives = 54/104 (51%), Gaps = 5/104 (4%) |
Tair |
Show Blast
|
| AT2G29150.1 |
| Symbols: | tropinone reductase, putative / tropine dehydrogenase, putative | chr2:12542792-12544041 REVERSE
Evalue: 7e-07 | Bitscore: 52
Identities = 55/176 (31%), Positives = 80/176 (45%), Gaps = 12/176 (6%) |
Tair |
Show Blast
|
| AT2G29340.1 |
| Symbols: | short-chain dehydrogenase/reductase (SDR) family protein | chr2:12604208-12606086 FORWARD
Evalue: 3e-06 | Bitscore: 50
Identities = 36/103 (34%), Positives = 56/103 (54%), Gaps = 5/103 (4%) |
Tair |
Show Blast
|
| AT2G29340.3 |
| Symbols: | short-chain dehydrogenase/reductase (SDR) family protein | chr2:12604208-12605105 FORWARD
Evalue: 3e-06 | Bitscore: 50
Identities = 36/103 (34%), Positives = 56/103 (54%), Gaps = 5/103 (4%) |
Tair |
Show Blast
|
| AT2G29340.2 |
| Symbols: | short-chain dehydrogenase/reductase (SDR) family protein | chr2:12604208-12605383 FORWARD
Evalue: 3e-06 | Bitscore: 50
Identities = 36/103 (34%), Positives = 56/103 (54%), Gaps = 5/103 (4%) |
Tair |
Show Blast
|
| AT2G29360.1 |
| Symbols: | tropinone reductase, putative / tropine dehydrogenase, putative | chr2:12610926-12612198 FORWARD
Evalue: 4e-06 | Bitscore: 50
Identities = 37/95 (38%), Positives = 51/95 (53%), Gaps = 5/95 (5%) |
Tair |
Show Blast
|
Gene Structure
View in GenomeView| View in Artemini
Download gene in EMBL format
- Structure
- Sequence Type
- mRNA
- Strand
- +
- Structure Quality
- 2
Protein
Associated ESTs/cDNAs
- n/a
-
|
