family Nr COG description functional class** gene name copy nr***
157 Uridylate kinase  F PyrH 1.02
228 Ribosomal protein S17  J RpsQ 1
351 Metal-dependent proteases with possible chaperone activity  O QRI7 1
453 Translation initiation factor 1 (IF-1)  J InfA 1.02
471 Ribosomal protein S11  J RpsK 1
602 Glycine/serine hydroxymethyltransferase  E GlyA 1.22
695 Ribosomal protein L4  J RplD 1
833 Ribosomal protein S5  J RpsE 1
849 Chaperonin GroEL (HSP60 family)  O GroL 1.3
959 Ribosomal protein S15P/S13E  J RpsO 1.01
1251 Glutamyl- and glutaminyl-tRNA synthetases  J GlnS 1.1
1441 Methionine aminopeptidase  J Map 1.28
1449 Translation initiation factor 3 (IF-3)  J InfC 1.01
1532 NAD-dependent DNA ligase (contains BRCT domain type II)  L Lig 1.03
1608 Ribosomal protein L13  J RplM 1
1694* replicative DNA helicase; intein/homing endonuclease L DnaB; - 1.11
1735 Ribosomal protein S10  J RpsJ 1
1807 5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase  H FolD 1.05
2015 Ribosomal protein L19  J RplS 1
2137 Phenylalanyl-tRNA synthetase alpha subunit  J PheS 1
2398 CTP synthase (UTP-ammonia lyase)  F PyrG 1
2497 Ribosomal protein L22  J RplV 1
2743* signal recognition particle GTPase U FtsY; Ffh 2.01
2754 Ribosomal protein L7/L12  J RplL 1
2930 tRNA-(guanine-N1)-methyltransferase  J TrmD 1
3092 Uncharacterized conserved protein  S   1.15
3225 Dimethyladenosine transferase (rRNA methylation)  J KsgA 1.1
3291 tmRNA-binding protein  O SmpB 1
3631 Ribosomal protein L2  J RplB 1
3647* thioredoxin reductase; thiol-disulfide isomerase + thioredoxin OC TrxA; TrxB 1.42
3696* EMAP domain; Methionyl-tRNA-synthetase R; J ARC1;MetG 1.04
3715 Enolase  G Eno 1.05
3753 Mg-dependent DNase  L TatD 1.45
3787 Aspartyl-tRNA synthetase  J AspS 1.01
3833 3-phosphoglycerate kinase  G Pgk 1
3946* Guanylaat kinase; Uncharacterised component of phosphonate metabolism F; P Gmk; - 1.17
4412* histidyl-tRNA-synthethase; - J; E HisS; HisZ 1.13
4728 Ribosomal protein S16  J RpsP 1
4991* DNA-directed RNA polymerase sigma subunit; specialised sigma subunit K RpoD; FliA 3.02
5044 Alanyl-tRNA synthetase  J AlaS 1
7522 ATP-dependent Zn proteases  O HflB 1.24
10112 DNA polymerase III, alpha subunit  L DnaE 1.26
12204 Pentose-5-phosphate-3-epimerase  G Rpe 1.23
13831 Ribosomal protein L9  J RplI 1
16270 Ribosomal protein L24  J RplX 1
16746 Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase  G GapA 1.57
20044 Methionyl-tRNA formyltransferase  J Fmt 1.02
21512 Co-chaperonin GroES (HSP10)  O GroS 1.13
31509* DNaJ-class molecular chaperone; idem with c-term Zn-finger domain O CbpA; DNaJ 1.48
31578 Ribosomal protein S14  J RpsN 1.21
31598 Nuclease subunit of the excinuclease complex  L UvrC 1.02
31738 Ribosomal protein L17  J RplQ 1
31762 Isoleucyl-tRNA synthetase  J IleS 1.03
31782* Topoisomerase A related L TopA 1.01
31925 Cysteinyl-tRNA synthetase  J CysS 1.08
32194 Ribosomal protein S18  J RpsR 1.04
32323 Arginyl-tRNA synthetase  J ArgS 1.02
32496* Ribosomal protein L21; - J   1
32554* Phosphotransferase system IIB components; triosephosphate isomerase G PtsG; TpiA 1.08
33097 Ribosomal protein L33  J RpmG 1.28
33745 Predicted tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase  J TrmU 1.05
34027 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases  FGR Hit 1.11
34678 Ribosomal protein L35  J RpmI 1
35599 rRNA methylases  J SpoU 1.75
* more than one COG in this family
** full descriptions of functional classes can be found here http://www.ncbi.nlm.nih.gov/COG/
*** copy nr = average number of genes per strain