Gene duplication and biased functional retention of paralogs in bacterial genomes
Dirk Gevers, Klaas Vandepoele, Cedric Simillion and Yves Van de PeerCorresponding author:
Gene duplication is considered an important prerequisite for gene innovation that can facilitate adaptation to changing environments. The analysis of 106 genome sequences shows a significant number of paralogs in all bacterial genomes. Analysis of the functional classification of these paralogs reveals a preferential enrichment in functional classes that are involved in transcription, metabolism and defense mechanisms. From the organization of paralogs in the genome we can conclude that duplicated genes in Bacteria seem to have mainly been created by small scale duplication events such as tandem and operon duplications.
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