Grigoris Amoutzias

Postdoc (Group member since 2007) + 32 (0) 9 33 13 810 VIB / Ghent University Bioinformatics & Systems Biology Technologiepark 927 B-9052 Gent BELGIUM

CV

• February 2008: EMBO long-term fellow.
• July 2007 - present: Postdoctoral researcher at the Bioinformatics and Evolutionary Genomics Group, Department of Plant Systems Biology, UGent & VIB, Gent, Belgium.
• April 2007 - July 2007: Visiting scientist at the Institute of Agrobiotechnology, INA, EKETA, Thessaloniki, Greece
• September 2005 - April 2007: First assistant in the Department of Ecology and Evolution, Faculty of Medicine and Biology, University of Lausanne.
• September 2001 - September 2005: PhD in Bioinformatics, Manchester University, UK
• March 2004 - August 2004: Six month research project in text mining, in the Pathways group, in pharmaceutical company AstraZeneca PLC, Macclessfield, UK and Waltham, MA, USA
• September 2000-September 2001: MRes in Bioinformatics, Leeds University, UK
• September 1998-February 1999: Exchange student with Socrates programme, Queen's University of Belfast, UK
• September 1994-July 1999: Bsc in Biology, Aristotle University of Thessaloniki, Greece.

Research

• Text mining, data integration, evolution and functional consequences of protein-interaction (especially dimerization) networks in transcription factors.
• Secondary metabolites in prokaryotes and fungi.

Papers

(18) Amoutzias, G., Van de Peer, Y. (2010) Single-Gene and Whole-Genome Duplications and the Evolution of Protein-Protein Interaction Networks. (in press).

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(17) Amoutzias, G., He, Y., Gordon, J., Mossialos, D., Oliver, S., Van de Peer, Y. (2009) Post-translational regulation has a major impact on the fate of duplicated genes. Proc Natl Acad Sci (in press).

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(16) Amoutzias, G., Van de Peer, Y., Mossialos, D. (2008) Evolution and taxonomic distribution of nonribosomal peptide and polyketide synthases. Future Medicine 3, 361-70.

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(15) Amoutzias, G., Van de Peer, Y. (2008) Together We Stand: Genes Cluster to Coordinate Regulation. Dev. Cell. 14, 640-2.

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(14) Amoutzias, G., Robertson, D., Van de Peer, Y., Oliver, S. (2008) Choose your partners: dimerization in eukaryotic transcription factors. Trends in Biochemical Sciences 33, 220-9.

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(13) Pampalakis, G., Arampatzidou, M., Amoutzias, G., Kossida, S., Sotiropoulou, G. (2007) Identification and analysis of mammalian KLK6 orthologue genes for prediction of physiological substrates. Comput Biol Chem. Nov 29.

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(12) Pinney, J., Amoutzias, G., Rattray, M., Robertson, D. (2007) Reconstruction of ancestral protein interaction networks for the bZIP transcription factors. Proc. Natl. Acad. Sci. USA 104, 20449-53.

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(11) Holden, B., Pinney, J., Lovell, S., Amoutzias, G., Robertson, D. (2007) An exploration of alternative visualizations of the basic helix-loop-helix protein interaction network. BMC Bioinformatics 8, 289.

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(10) Amoutzias, G., Pichler, E., Slomianny, M.C., De Graaf, D., Imsiridou, A., Robinson-Rechavi, M., Bornberg-Bauer, E., Robertson, D., Oliver, S. (2007) A protein interaction atlas for the nuclear receptors: Properties and quality of a hub-based dimerisation network. BMC Systems Biology 1, 34.

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(9) Mossialos, D., Amoutzias, G. (2007) Siderophores in fluorescent pseudomonads: new tricks from an old dog. Future Microbiology 2, 387-95.

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(8) Amoutzias, G., Veron, A., Weiner, J., Robinson-Rechavi, M., Bornberg-Bauer, E., Oliver, S., Robertson, D. (2006) One Billion Years of bZIP Transcription Factor Evolution: Conservation and Change in Dimerization, and DNA-Binding Site Specificity. Mol. Biol. Evol. 23, 2259-2532.

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(7) Amoutzias, G., Bornberg-Bauer, E., Oliver, S., Robertson, D. (2006) The Reduction/oxidation-phosphorylation control of the DNA binding of the bZIP family is linked with its dimerization network. BMC Genomics 4, 7-107.

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(6) Amoutzias, G., Weiner, J., Bornberg-Bauer, E. (2005) Phylogenetic profiling of protein interaction networks in eukaryotic transcription factors reveals focal proteins being ancestral to hubs. Gene Feb 23 .

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(5) Podowski, R., Cleary, J., Goncharoff, N., Amoutzias, G., Hayes, R.D. (2005) Suregene, a scalable system for automated term disambiguation of gene and protein names. . J Bioinform Comput Biol 3, 743-70.

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(4) Amoutzias, G., Robertson, D., Oliver, S., Bornberg-Bauer, E. (2004) Convergent evolution of gene networks by single-gene duplications in higher eukaryotes. EMBO Rep. 5, 274-9.

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(3) Amoutzias, G., Robertson, D., Bornberg-Bauer, E. (2004) The evolution of protein interaction networks in regulatory proteins. Comp Func Genomics 5, 79-84.

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(2) Podowski, R., Cleary, J., Goncharoff, N., Amoutzias, G., Hayes, R.D. (2004) AZuRE, a scalable system for automated term disambiguation of gene and protein names. Proc IEEE Comput Syst Bioinform Conf 415-24.

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(1) Imsiridou, A., Hardy, H., Maudling, N., Amoutzias, G., Zaldivar Comenges, J. (2003) Web database of molecular genetic data from fish stocks. J Hered 94, 265-7.

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